Changes in Serum Mineral Markers in Menopausal Women

Author: Dr. Rupali Bahduri[1], Dr. Amiya Goswami[2]

[1]Asst. Prof RVHMC, JRNRV University,

[2]Dean and Director, RVHMC&H,


Address for correspondence:

Dr. Amiya Goswami

JRNRV University, Dabok, Udaipur,

No.:- 09351343740 ,


Menopause is the transition phase of a women’s life and of vital significan0ce where several changes occur in the whole body including the serum mineral levels. Various symptoms and signs are seen to accompany this transition period. Knowledge of changes of internal bio mineral markers will not only enhance our knowledge but also will help in providing essential management during this phase of a women’s life.

Key words– menopause, serum calcium, serum magnesium, serum copper,serum phosphates, serum ferritin, trace elements.


Menopause is a transition phase from reproductive to the non-reproductive phase in women’s life. Menopause is the nature’s protective phenomena against the reproductive morbidity and mortality in ageing population. It sets the stage of aging and accelerates the process of non communicable disease.The menopause is simply one event in the whole range of anatomical physiological and psychological events that contribute to climacteric. Derived from the Greek word klimakter(rung of a ladder)the climacteric was so termed to describe a major movement on life’s ladder1.

The word ‘menopause’ was coined by the French physician C.P. Cole Gardonne in 1816 and is derived from two words, ‘meno’ (month) and ‘paus’ (to stop). Clinically, menopause is said to have occurred when menstruation has ceased for twelve months. Physiologically, menopause is defined as the permanent cessation of menses resulting from reduced ovarian hormone secretion that occurs naturally or is induced by surgery, chemotherapy, or radiation. The post-menopausal stage in women is essentially an oestrogen-deficient state. Both menopause and aging are associated with an accelerated loss of bone mass. Menopause occurs when the balance between bone formation and resorption is upset and resorption is excessive, resulting in a negative remodelling balance2.

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