Breast Cancer Cells are more Sensitive to the Treatment with Homeopathic Viscum Album (200CH) than Mesenchymal Stem Cells.

Ana Catarina Viana Valle1,2, Hilana dos Santos Sena Brunel3, Patricia Furtado Malard3,

Lana Ribeiro Aguiar3, Rosângela Vieira de Andrade1

1Post Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brazil.

2IDIS Lamasson, DoctorIzao Soares Institute, Brazil.

3BioInnova Laboratory, Brazil.

Address for Correspondence:

Ana Catarina Viana Valle

Catholic University of Brasilia, Postal Code: 71680-613, Brasília, DF, Brazil.

Email: dranacatarina@gmail.com

E-mail addresses of all authors:

Hilana dos Santos Sena Brunel: lanasena@gmail.com

Patrícia Furtado Malard: patricia@biocell.com.br

Lana Ribeiro Aguiar: lanaribeiroaguiar@gmail.com

Rosângela Andrade: rosangelavand@gmail.c

Abstract

Studying adenocarcinoma cells and the new therapies to treat cancer is a promising area of interest. Adenocarcinoma in breast can be of several types, and different cell lines are in use because they have several characteristics similar to those of mammary epithelium but with different severities and phenotypes, consolidated as an in vitro model to study breast cancer biology. As breast cancer is the commonest cause of cancer death in women worldwide, new possibilities of therapies should be researched, suchas the homeopathic Viscum album, a medicine originated from a plant whichextract has cytotoxic effects. In this study, MCF-7, SKBR-3, MDA-MB-321 and PMC-42 cell lines as well as Mesenchymal Stem Cells (MSC)were cultured in the presence of homeopathic Viscum album1×10-400(VA200CH). Cell viability was evaluated by MTT assay and compared between the cell lines.