Effect of Homoeopathic Medicine Cephalandra Indica on Glucose Metabolism, β cell Function and Insulin Resistance in Adults of Type 2 Diabetes: Double Blind, Placebo Controlled Cross Over Study

Effect of Homoeopathic Medicine Cephalandra Indica on Glucose Metabolism, β cell Function and Insulin Resistance in Adults of Type 2 Diabetes: Double Blind, Placebo Controlled Cross Over Study

Sulemani A Aijaz1, Singh Neetu2, Agrawal RP3, Vivekanand Kumar4

1Principal
Mangi Lal Nirban Homoeopathic Medical College and RI, Bikaner
2Professor and HOD, Dept. of OBS and GYN,
Mangi Lal Nirban Homoeopathic Medical College and RI
3Principal Investigator
Diabetic Care and Research Centre, SP Medical College Bikaner
4R.O ,CCRH, H/Q New Delhi
Address for correspondence
Sulemani A Aijaz
Mangi Lal Nirban Homoeopathic Medical College and RI
Bikaner

ABSTARCT

Background: To assess the efficacy of homoeopathic medicine Cephalandra indica on glucose metabolism, b cell function and insulin resistance in adults of type 2 diabetes.

Methods: 100 patients were enrolled in the study and categorized into 2 groups, group I and group II. After one month of stabilization period Group I were given Homoeopathic medicine Cephalandra Indica and Group II with Placebo; followed by one month washout period. Afterwards regimen was interchanged for 6 months. Biochemical and anthropometric data was recorded at baseline, at 3rd month and at 6th month, after stabilization, before and after washout and at the end of study.

Results: An improving trend was observed in both the groups for Cephalandra Indica Q (FBS- 176.32±17.08 to 130.82±3.55 mg/dl p< 0.05 in group I and FBS 185.60±27.61 to 140.28±10.37 in group II). HbA1C improved due to Cephalandra Indica in group I (7.96±1.08 to7.40±.65) & in group II (8.23±1.07 to 6.77±.54). The HOMA IR reduced from 8.92±2.20 to 5.78±1.44 in group I as well as 11.44±5.03 to 6.88 in group II & HOMA Beta cell function improved from 66.03±16.62 to 95.10±23.69 in group I and 77.36±43.19 to 93.43±33.75 in group II.

Conclusion: In freshly diagnosed type-2 diabetics Cephalandra indica reduced FBS, HbA1c, Insulin resistance and also significantly increased the beta cell functioning. It shows hypoglycemic effect of Cephalandra indica.

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